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Sean Penn Reacts to Nikki Glaser Calling Him a “Sexy Leather Handbag”

Sean Penn Reacts to Nikki Glaser Calling Him a “Sexy Leather Handbag” thumbnail

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When it came her Golden Globes 2026 opening monologue, Nikki Glaser had it in the bag.

In addition to Leonardo DiCaprio, George Clooney and Kevin Hart, the comedian also roasted Sean Penn as she took the stage inside the Beverly Hilton in Los Angeles Jan. 11. (Click here to see all the red carpet arrivals.)

“Everyone in this town is obsessed with looking younger, but Sean Penn is like, ‘What if I slowly morph into a sexy leather handbag?'” Nikki quipped, before the camera panned to the 65-year-old laughing and nodding from his seat. “It’s hot. It’s good.”

The two-time Golden Globes host also had some fun with Sean’s transformation into a “devoted humanitarian.”

“I feel like a lot of actors talk the talk, but Sean Penn will actually go to the places in the world that need help the most,” she said, “and he will do cocaine there.”

As the One Battle After Another star broke out into laughter, Nikki continued, “Sean, I did get permission to do that joke from your two best friends Charlie Sheen and El Chapo.”

But Nikki, 41, knows when to draw the line at her digs about A-listers.

“You have to be very delicate about making jokes that aren’t going to ruin anyone’s night,” she told E! News earlier in January. “But you also want to give the people at home something to laugh at, and you want to poke fun at the people that they’re dying for you to make fun of. People at home want you to make fun of the A-listers.”

Kevin Mazur / Contributor / GETTY IMAGES

However, there’s one celebrity she completely refuses roast: Julia Roberts. As she put it, “You cannot make fun of America’s Sweetheart.”

That’s why at this year’s ceremony, airing on CBS and streaming on Paramount+, she opted for a self-deprecating joke when addressing the Pretty Woman alum.

“And just like the podcasters nominated tonight,” she told the crowd, “I should not be allowed to be this close to Julia Roberts.”

To see all the stars at the 2026 Golden Globes, read on…

Monica Schipper / Staff / GETTY IMAGES

Jennifer Lopez

in vintage Jean-Louis Scherrer and Christian Louboutin. 

David Fisher/Shutterstock

Owen Cooper

in Bottega Veneta. 

Monica Schipper / Staff / GETTY IMAGES

Dakota Fanning

in Vivienne Westwood and Fred Leighton jewelry.  

Frazer Harrison / Staff / GETTY IMAGES

Orlando Bloom

in Berluti. 

Amy Sussman/Getty Images

Jennifer Lawrence

in custom Givenchy. 

Kevin Mazur/Getty Images

Hailee Steinfeld

David Fisher/Shutterstock

Rose Byrne

in Chanel. 

Kevin Mazur/Getty Images

Amanda Seyfried

in Versace. 

David Fisher/Shutterstock

Ariana Grande

in custom Vivienne Westwood.

Kevin Mazur/Getty Images

Julia Roberts

in custom Armani Privé. 

Amy Sussman / Staff / GETTY IMAGES

Priyanka Chopra Jonas & Nick Jonas

in custom Christian Dior and Bvlgari jewelry (Chopra Jonas) and Berluti (Jonas). 

Monica Schipper / Staff / GETTY IMAGES

Alicia Silverstone

in Nicole + Felicia. 

Amy Sussman / Staff / GETTY IMAGES

Wunmi Mosaku

in Matthew Reisman Collection and Messika High Jewelry.  

David Fisher/Shutterstock

Ginnifer Goodwin

in Giorgio Armani Privé. 

Amy Sussman / Staff / GETTY IMAGES

Ayo Edebiri

in Chanel. 

Frazer Harrison / Staff / GETTY IMAGES

Abby Elliott

in Valentino. 

Amy Sussman / Staff / GETTY IMAGES

Glen Powell

in Brunello Cucinelli and Omega watch. 

Amy Sussman / Staff / GETTY IMAGES

Jennifer Garner

in custom Cong Tri. 

Amy Sussman/Getty Images

Leighton Meester & Adam Brody

in Mui Mui and Kendra Scott Jewelry (Meester) and Valentino, Jaeger-LeCoultre watch and Allen Edmonds shoes (Brody). 

Matt Baron/BEI/Shutterstock

Danny Fujikawa & Kate Hudson

in custom Armani Privé and Garatti jewelry.

Kevin Mazur / Contributor / GETTY IMAGES

Nikki Glaser

in Zuhair Murad. 

Amy Sussman/Getty Images

Dax Shepard & Kristen Bell

in Armani Privé. 

Monica Schipper/Getty Images

John Krasinski & Emily Blunt

in Dolce & Gabbana (Krasinski) and custom Louis Vuitton and Tiffany & Co. jewelry. 

Kevin Mazur/Getty Images

Jenna Ortega

in Dilara Findikoglu. 

Kevin Mazur/Getty Images

Selena Gomez

in Chanel. 

Frazer Harrison / Staff / GETTY IMAGES

Elle Fanning

in Gucci and Cartier jewelry. 

Amy Sussman / Staff / GETTY IMAGES

Tessa Thompson

in Balenciaga.

Amy Sussman / Staff / GETTY IMAGES

Teyana Taylor

in custom Schiaparelli Haute Couture and Tiffany & Co. jewelry. 

Gilbert Flores/2026GG / Contributor / GETTY IMAGES

Leonardo DiCaprio

in Dior. 

Gilbert Flores/2026GG / Contributor / GETTY IMAGES

Charlie Hunnam

in Saint Laurent.

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