Grey’s Anatomy Reveals Surprise Pregnancy After Character’s Death
Amelia Shepherd is taking some time away from Grey Sloan Memorial Hospital.
The Grey’s Anatomy character, played by Caterina Scorsone, shared during the Oct. 16 episode of the show that she was going to take a sabbatical following the tragic explosion at the hospital in the season 21 finale that killed Dr. Monica Beltran (Natalie Morales) in the season 22 premiere.
However, the actress’ absence won’t be too long as E! News has learned that following a brief hiatus, her character will return to the operating room in 2026.
The series revealed that Amelia would be taking a sabbatical from her neurosurgery role during the drama’s milestone 450th episode.
And as the show continues to prosper, creator Shonda Rhimes has gotten candid about how she never imagined it would get this far—and now, she’s not sure how or when it will ultimately wrap up.
“I’d say back around episode 150 I knew how it was gonna end,” Shonda, who stepped down as showrunner in 2015, told Today’s Craig Melvin on the Oct. 13 episode of the NBC morning show. “Now we’re at 450—I have no idea. I mean, I wasn’t sure we’d get past season four or five. So the fact that we’re here in 22, season 22, is insane.”
Over the last two decades, she’s learned the key to success when it comes to a show with so many revolving characters is focusing on the story as a whole.
“I’m very committed to the story and not the character,” she shared, “but that does mean people die.”
Monica Schipper/FilmMagic
However, regardless of how everything plays out in the end, the How to Get Away With Murder creator noted, “I want everybody to end in a really positive, great way.” Because to her, that’s what the fans deserve.
“They’ve kept watching the show,” Shonda gushed, “and they’ve stuck with it, and they’re excited and invested.”
For more shocking Grey’s Anatomy moments, read on.
(E! and Today are both part of the NBCUniversal family.)
ABC
From Booty Call to Boss
Incoming surgical intern Meredith Grey (Ellen Pompeo) was thrown for quite a loop in Grey’s Anatomy‘s series premiere when she learned that the hunky one-night-stand she picked up at the bar played by Patrick Dempsey was actually her new boss, renowned surgeon Dr. Derek Shepherd. Oops.
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Addison’s Arrival
Fans were just as stunned as poor Meredith in the season one finale when Addison Montgomery (Kate Walsh) waltzed into Seattle Grace and right up to Mer and Derek, introducing herself with the now iconic “You must be the woman who’s been screwing my husband.”
Peter “Hopper” Stone/Walt Disney Television via Getty Images
Bombs Away
When Grey’s Anatomy was given the plum post-Super Bowl slot in its second season, fans watched tensely as Meredith decided to shove her hand into a body cavity containing a live explosive to keep it from detonating. And just as we began to breathe a sigh of relief when bomb squad chief Dylan (guest star Kyle Chandler) began to walk away with the removed explosive, it blew, taking the poor guy out in the process.
Scott Garfield/Disney General Entertainment Content via Getty Images
Denny’s Demise
Fans watched as Izzie (Katherine Heigl) fell in love with the effortlessly charming Denny Duquette (Jeffrey Dean Morgan) as he awaited a much-needed heart transplant throughout the second half of season two, falling for him right along with her. And when her wild plan to cut his LVAD wire to move him up the transplant list failed spectacularly, resulting in his death in the season finale, it was confirmed that Grey’s Anatomy was not here to give us the happy endings we wanted.
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Meredith’s Near-Death Experience
What was more surprising during season three’s big ferry accident: Meredith nearly drowning after being knocked into freezing cold waters at the accident site or her later admission that she’d given up trying to survive?
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Lexie’s Arrival
At the end of season three, a surgical intern named Lexie (Chyler Leigh) arrived at Seattle Grace, first meeting Derek the night prior to starting at the hospital in a moment that mirrored his first interaction with Mer two seasons prior (but, thankfully, did not end with them sleeping together) and then introducing herself to George O’Malley (T.R. Knight) in the intern locker room. Oh, and her last name? Why, Grey, of course. And just like that, Meredith’s younger half-sister, one of two daughters raised by her father Thatcher and his second wife Susan, was added to the mix.
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Ghost Denny
Two and a half seasons after he’d perished, Denny was back and his ghost was…having sex with Izzie. In one of the most ludicrous moments in the show’s history, Ghost Denny was used to signal to viewers and to Izzie herself that something was wrong. That something was ultimately proven to be stage IV metastatic melanoma, which had spread to, among other places, her brain.
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It’s George
While fans were expecting Izzie to bite the bullet in the season five finale, the fact that no one could find George should’ve clued us into the fact that something was up with poor O’Malley. When Meredith finally realized what the John Doe who’d been hit by a bus while trying to save a woman on the street was writing in her hand–007, his cruel nickname in earlier seasons–she tried to alert the surgeons working on him, but it was too late. He flatlined and died.
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The Shooting
File this one under: The mist disturbing episode in Grey’s history. In the season six finale, the grieving husband of a deceased patient arrived at the hospital, fresh off its merger with neighboring Mercy West, with a loaded gun and nothing left to live for. A few doctors were murdered, several more injured, and the image of Bailey (Chandra Wilson) being dragged by her feet out from under a patient’s bed will forever haunt us. Thankfully, she survived. Mer and Derek’s baby wasn’t so lucky. After he was shot, she believed he’d died and had a traumatic miscarriage.
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The Plane Crash
Two seasons after the horrific hospital shooting, Shonda Rhimes decided it was time to torture a handful of docs yet again. In the eighth season finale, a plane carrying Meredith, Derek, Cristina Yang (Sandra Oh), Lexie, Mark Sloan (Eric Dane) and Arizona Robbins (Jessica Capshaw), traveling to Boise, Idaho to perform surgery on conjoined twins, crashed in the wilderness, leaving them stranded and wounded, with no one at home even knowing they’d gone down. The accident claimed Mark and Lexie’s lives and Arizona’s leg, while nearly leaving Derek’s hand permanently injured.
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Burke’s Return
How would Grey’s send off Mer’s person Cristina at the end of season 10 after Sandra Oh decided to move on? Why, by having ex Preston Burke (Isaiah Washington) pop back up after leaving her at the altar in season three to offer her his hospital in Switzerland. That the show brought Washington back after his highly contentious exit, which involved him referring to co-star T.R. Knight by a heinous gay slur, was truly surprising.
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Maggie’s Arrival
As the show said goodbye to Cristina in the season 10 finale, it welcomed her replacement as the head of cardio-thoracic surgery, Dr. Maggie Pierce. And when the character, played by Kelly McCreary, revealed to Richard (James Pickens Jr.) in the episode’s final moments that she was Dr. Ellis Grey’s daughter, asking if he knew the legendary doctor, he wasn’t the only one stunned to learn that he had a daughter and that Mer had another sister.
ABC/Kelsey McNeal
Derek’s Departure
Literally no one saw it coming when, with a handful of episodes left to air in season 11, Derek was killed off, the victim of a head-on collision just after rescuing a family on the side of the road involved in a car crash of their own. Patrick Dempsey had just recently extended his contract on the show, making his departure truly unexpected. Killing off Mer’s husband may have been Shonda Rhimes‘ only feasible option to get rid of the character in a way that didn’t render an 11-year love story completely worthless, but that didn’t mean it hurt any less.
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Meredith’s Attack
As if Mer hadn’t been through enough up to this point, in the ninth episode of season 12, she was violently attacked by a patient in a brutal episode that saw her jaw broken and then wired shut in order to restore her hearing. Her panic attack when her kids won’t see her during her recovery was a stunning moment of acting from Ellen Pompeo.
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Alex’s Departure
How would the show explain Alex Karev’s sudden absence after original star Justin Chambers walked away from his role midway through season 16? By having him write letters to wife Jo (Camilla Luddington), Mer and Bailey explaining that he’d gotten in contact with Izzie years after she ghosted and sent him divorce papers, only to learn that she’d been raising their twins all these years on a farm somewhere and he’d chosen his newfound family over his life in Seattle. If anyone tells you they saw that coming, we’ll show you a liar.
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The Death of Dr. DeLuca
In season 17, fans watched as Dr. Andrea “Andrew” DeLuca (Giacomo Gianniotti) met his untimely end. After overcoming his mental health struggles, DeLuca found himself as an attending at Grey Sloan Memorial Hospital. Yet, in typical Grey’s fashion, Dr. DeLuca’s back-on-track life was cut tragically short when he was stabbed by a human trafficker’s accomplice.
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